Radiation therapy for extrahepatic bile duct cancer: Current evidences and future perspectives

Table 4 Palliative radiotherapy for stent patency in hilar cholangiocarcinoma

Ref.	Study period	Study design	No. of pts	EBRT	Brachytherapy	Median OS (mo)		Median stent patency (mo)
Lee et al[60]1	2005-2008	Retrospective	18	≥ 50 Gy	-	14.0	P = 0.11	4.7	P = 0.94
			32	-	-	9.0		4.5
Isayama et al[59]	1986-2008	Retrospective	28	Median 50 Gy	24 Gy (n = 11)	22.1	P = 0.0031	50%2	P = 0.0165
			11	-	-	5.7		0%2
Shinchi et al[61]	1992-1998	Retrospective	30	Median 46 Gy3	-	10.63	P < 0.05	9.83	P = 0.0002
			10	-	-	6.43		3.73
Tan et al[62]	2007-2013	Retrospective	25	37.0-40.7 Gy	-	12.2	P = 0.025	10.9	P = 0.022
			13	-	-	8.9		6.5

¹Location not specified;

²Crude stent patency rate at 1-yr;

³mean. ERRT: External beam radiotherapy; OS: Overall survival.