Copyright
©The Author(s) 2018.
World J Clin Cases. Aug 16, 2018; 6(8): 224-232
Published online Aug 16, 2018. doi: 10.12998/wjcc.v6.i8.224
Published online Aug 16, 2018. doi: 10.12998/wjcc.v6.i8.224
Table 1 Prediction of protein function using different softwares
| Gene | Polyphen-2_HDIV | Polyphen-2_HVAR | MutationTaster | FATHMM | M-CAP | |||||
| Score | Prediction | Score | Prediction | Score | Prediction | Score | Prediction | Score | Prediction | |
| MSH6 | 0.670 | Possibly damaging | 0.411 | Benign | 1 | Disease causing | -2.12 | Damaging | - | - |
| APC | 0.156 | Benign | 0.026 | Benign | 0.737 | Disease causing | -2.47 | Damaging | 0.046 | Damaging |
- Citation: Duan FX, Gu GL, Yang HR, Yu PF, Zhang Z. Must Peutz-Jeghers syndrome patients have the LKB1/STK11 gene mutation? A case report and review of the literature. World J Clin Cases 2018; 6(8): 224-232
- URL: https://www.wjgnet.com/2307-8960/full/v6/i8/224.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v6.i8.224