High prevalence of cholestasis, with increased conjugated bile acids in inflammatory bowel diseases patients

Table 2 Univariate analysis¹n (%)

	TBA > 8	TBA < 8	P value
	(n = 80)	(n = 1190)
TBA (mean ± SD, μmol/L)	14.66 ± 1.24	3.07 ± 0.06	6.15 × 10-144
Alkaline phosphatase (mean ± SD, U/L)	81 ± 5.81	69.3 ± 1.25	0.021
Albumin (mean ± SD, g/L)	38.0 ± 0.92	39.9 ± 0.21	0.017
Vitamin D	25 (31)	254 (21)	0.038
Vitamin E	2 (3)	9 (1)	0.103
Calcium	30 (38)	336 (28)	0.076
Prednisone	16 (20)	160 (13)	0.100
Azathioprine	37 (46)	383 (32)	0.009
Smokers	12 (15)	330 (28)	0.012
Thrombosis	4 (5)	17 (1)	0.015

¹Results expressed in number with percentage in parenthesis otherwise stated. Univariate analysis of factors differentiating patients with or without cholestasis. TBA: Total bile acid; SD: Standard deviation.