Combined silicosis and mixed dust pneumoconiosis with rapid progression: A case report and literature review

Figure 2 Histopathologic findings of lung biopsy specimen. A: Lung parenchyma was replaced by diffuse infiltration of phagocytic macrophages with focal areas of sclerosis (original magnification, ×100); B: Macrophages contained anthracotic pigment and rare multinucleated giant cells (original magnification, ×400); C: Polarized microscopic examination revealed many birefringent crystals (original magnification, ×400).