Genetic associations of inflammatory bowel disease in a South Asian population

Table 4 Association of single nucleotide polymorphisms with clinical characteristics of ulcerative colitis and Crohn’s disease

Characteristic	SNPs	OR1	P	95%CI
Risk for UC	rs11805303	1.35	0.009	1.08	1.69
Extensive disease in UC	rs9268853	0.59	0.009	0.37	0.82
Upper GI disease in CD	rs10045431	4.42	0.002	1.75	12.92
Mild disease in UC	rs886774	1.66	< 0.001	1.13	2.17
Maintained UC remission	rs886774	1.48	< 0.001	1.19	1.85
Use of biologics in CD	rs9268853	3.36	0.004	1.48	7.58

¹Univariate odds for the presence of single nucleotide polymorphisms in patients with characteristics tested against healthy controls. OR: Odds ratio; SNPs: Single nucleotide polymorphisms; GI: Gastrointestinal; CD: Crohn’s disease; UC: Ulcerative colitis.