Carney complex: Two case reports and review of literature

Table 1 Clinical features of Carney complex and some similar genetic syndromes

	Clinical features	Estimated incidence[7-13]
Carney complex	Lentigines	70%-80%
	Blue nevi	40%
	Cutaneous myxomas	Less than 50%
	Primary pigmented nodular adrenocortical disease	25%-45%
	Asymptomatic growth hormone hypersecretion	66%
	Large cell calcifying Sertoli cell tumors	75% of male patients
	Thyroid nodules	75%
	Cardiac myxomas	30%-72%
	Psammomatous melanotic schwannomas	18%
	Benign breast tumor	14% of female patients
	Osteochondromyxomas	< 1%
Peutz-Jeghers syndrome	Mucocutaneous pigmentation	More than 95%
	Hamartomatous polyps	Most of the patients
McCune-Albright syndrome	Peripheral precocious puberty	50% in females at 4 yr in de Sanctis C’s research
	Irregular café-au-lait skin pigmentation	Almost all the patients in de Sanctis C’s research
	Fibrous dysplasia of bone	50% at 8 yr of age in de Sanctis C’s research