Iron metabolism disorders in patients with hepatitis B-related liver diseases

Table 2 Factors associated with serum hepcidin concentration in multiple linear regression models

	Correlation analysis		Linear regression analysis
Characteristic	rho	P-value	Effect size	P -value
Age (yr)	0.3	< 0.01	0.213	0.001
Gender	0.01	0.986	-	-
ALT (U/L)	-0.095	0.141	-	-
AST (U/L)	-0.013	0.842	-	-
GGT (U/L)	0.011	0.871	-	-
AKP (U/L)	0.123	0.058	-	-
ALB (g/L)	-0.055	0.394	-	-
TBIL (μmol/L)	0.108	0.096	-	-
TBA (μmol/L)	0.196	0.002
HBV-DNA (Log10)	-0.374	< 0.01	-0.282	< 0.001
APRI	0.114	0.077	-	-
RBC (× 1012/L)	-0.153	0.018
WBC (× 109/L)	-0.119	0.065	-	-
PLT (× 109/L)	-0.195	0.002
HGB (g/L)	-0.158	0.014
MCV (fL)	0.01	0.879	-	-
HCT (L/L)	-0.162	0.012
INR	0.188	0.003	0.198	< 0.001
Serum iron (μmol/L)	0.027	0.672	-	-
Total iron binding capacity (μmol/L)	-0.073	0.261	-	-
Serum ferritin (μg/L)	-0.13	0.836	-	-
Transferrin saturation (%)	0.056	0.387	-	-
transferrin (g/L)	0.002	0.98	-	-

ALT: Alanine aminotransferase; AST: Aspartate transaminase; AKP: Alkaline phosphatase; ALB: Albumin; APRI: AST to platelet ratio index; HBV: Hepatitis B virus; TBIL: Total bilirubin; RBC: Red blood cell count; WBC: White blood cell count; TBIL: Total bilirubin; TBA: Total bile acid; HGB: Hemoglobin; HCT: Hematocrit; PLT: Platelets; MCV: Mean corpuscular volume; INR: International normalized ratio.