Review
Copyright ©The Author(s) 2018.
World J Clin Cases. Sep 26, 2018; 6(10): 322-334
Published online Sep 26, 2018. doi: 10.12998/wjcc.v6.i10.322
Table 5 Differential diagnosis of nail pigmentation
Causation of nail pigmentationCondition
Nonmelanocytic originExogenousDirt
Tobacco
Tar
Potassium hypermanganate
Silver nitrate
InfectiousBacterial infection
(e.g., Pseudomonas aeruginosa)
Onychomycosis
(fungal infection)
TraumaticSubungual hemorrhage
Subungual hematoma
NeoplasticHemangioma
Melanocytic originPhysiologicalEthnic (racial) melanonychia
NutritionalVitamin B12 deficiency
TraumaticOnychotillomania (nail biting)
Frictional melanonychia
IatrogenicSystemic drug-induced melanonychia
(e.g., zidovudine, hydroxyurea, and minocyline)
Radiotherapy-induced melanonychia
InflammatoryLichen planus
Psoriasis
EndocrinicAddison’s disease
Pregnancy
SyndromicLHS
AIDS
Activated melanocyticBenign melanocytic hyperplasia
Lentigo simplex
Nevus
NeoplasticOnychopapilloma
Onychomatricoma
Bowen’s disease
Melanoma