Feasibility of initial endoscopic common bile duct stone removal in patients with acute cholangitis

Table 1 Patient characteristics n (%)

	Initial group (n = 19)	Delayed group (n = 12)	P value
Age, median (IQR), yr	71 (62-80)	80 (74-84)	0.0641
Sex, male/female, n	11/8	6/6	0.6672
AC severity3, mild/moderate/severe, n	11/8/0	5/4/3	0.0722
CBD diameter, median (IQR), mm	9 (8-10)	11 (8-13)	0.1691
Number of CBD stones, single/multiple, n	9/10	6/6	0.8862
Diameter of CBD stone, < 10 mm/≥ 10 mm, n	15/4	9/3	0.7982
Periampullary diverticulum	9 (47)	4 (33)	0.4412
Use of antithrombotic agents before EBD	2 (11)	7 (58)	0.0042
Period until EBD from AC onset, < 24 h/24-48 h, n	11/8	8/4	0.6482
Blood CRP level before EBD, median (IQR), mg/dL	3.9 (1.4-6.7)	5 (1.6-12.2)	0.4291
Positive blood culture, n/total	6/14 (43)	5/7 (71)	0.2172

¹Mann-Whitney U test;

²χ² test;

³Tokyo Guidelines for the management of acute cholangitis (TG13). IQR: Interquartile range; AC: Acute cholangitis; CBD: Common bile duct; EBD: Endoscopic biliary drainage; CRP: C-reactive protein.