Copyright
©The Author(s) 2017.
World J Clin Cases. Jun 16, 2017; 5(6): 222-233
Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.222
Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.222
General | Rare tumor of uncertain origin and low malignant potential, composed of epithelioid cells, spindle cells, and ganglion-like cells |
Clinical features | Most often 5th-7th decade of life |
Most often abdominal pain or gastrointestinal bleeding | |
Gross findings | 90% occurring in second portion of duodenum |
10-90 cm in greatest dimension (average 30 cm) | |
Cytologic findings | Typically cellular specimen |
Epithelioid cells predominate | |
All three components may be present | |
Histologic findings | Epithelioid cells, spindle-like/sustentactular cells, and ganglion-like cells |
Submucosal | |
Unencapsulated | |
Necrosis absent | |
No to rare mitoses | |
Frequent extension beyond submucosa and/or lymphovascular invasion | |
Metastases: 75% of those reported demonstrated all three cellular components; 25% predominantly epithelioid |
- Citation: Cathcart SJ, Sasson AR, Kozel JA, Oliveto JM, Ly QP. Duodenal gangliocytic paraganglioma with lymph node metastases: A case report and comparative review of 31 cases. World J Clin Cases 2017; 5(6): 222-233
- URL: https://www.wjgnet.com/2307-8960/full/v5/i6/222.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v5.i6.222