Case Report
Copyright ©The Author(s) 2017.
World J Clin Cases. Jun 16, 2017; 5(6): 222-233
Published online Jun 16, 2017. doi: 10.12998/wjcc.v5.i6.222
Table 2 Pathologic features of gangliocytic paragangliomas found to have metastases
GeneralRare tumor of uncertain origin and low malignant potential, composed of epithelioid cells, spindle cells, and ganglion-like cells
Clinical featuresMost often 5th-7th decade of life
Most often abdominal pain or gastrointestinal bleeding
Gross findings90% occurring in second portion of duodenum
10-90 cm in greatest dimension (average 30 cm)
Cytologic findingsTypically cellular specimen
Epithelioid cells predominate
All three components may be present
Histologic findingsEpithelioid cells, spindle-like/sustentactular cells, and ganglion-like cells
Submucosal
Unencapsulated
Necrosis absent
No to rare mitoses
Frequent extension beyond submucosa and/or lymphovascular invasion
Metastases: 75% of those reported demonstrated all three cellular components; 25% predominantly epithelioid