Unique case of oligoastrocytoma with recurrence and grade progression: Exhibiting differential expression of high mobility group-A1 and human telomerase reverse transcriptase

Figure 3 Florescence based immunohistochemistry for analysis and interpretation of human telomerase reverse transcriptase expression. A: Expression of marker in the first resected sample (grade II); B: Signal intensity of the marker at first recurrence (grade II); C: Increased hTERT expression at second recurrence (grade II); D: Intense immune-reactivity at confined foci in last surgical sample resected classified as histopathological grade III. hTERT: Human telomerase reverse transcriptase.