Hepatitis C virus positive patient diagnosed after detection of atypical cryoglobulin

Figure 4 Cryoglobulin immunosubtraction was performed with V8 automated clinical capillary electrophoresis (Helena, United Kingdom). Arrows indicate specifically subtracted parts of immunoglobulins which mean cryoglobulin is composed of these. In this report, a mixed cryoglobulin is present: Monoclonal IgM kappa and polyclonal IgG and IgA heavy chains together with lambda light chain are detected (report shows heavy and light chains separately). Small frames indicate zoomed traces for monoclonal IgM kappa. Serum protein electrophoresis (SPE), shows total protein electrophoresis of cryoglobulin and an absent albumin band indicates washing and isolating of the cryoprecipitate is successfully performed.