Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis

Figure 4 Bacterial killing and IgG2b level. A: Bacterial killing assay was performed using bacteria obtained from cecal culture as described in the methods. Data represent mean ± SD of 3 independent experiments. Statistical analysis was performed using one-way analysis of variance with Tukey post hoc analysis. ^aP < 0.05; B: Serum IgG2b level was shown. Statistical analysis was performed using one-way variance of analysis with Tukey post hoc analysis. ^aP < 0.05, respectively of the comparison between wild-type vs CD11a knockout (KO) mice at the same time point, or comparison among wild-type or CD11a KO mice. N-WT: Wild-type neutrophils; N-KO: CD11a KO neutrophils; S-WT: Wild-type serum; S-KO: CD11a KO serum.