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©The Author(s) 2015.
World J Clin Cases. Jul 16, 2015; 3(7): 545-555
Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.545
Published online Jul 16, 2015. doi: 10.12998/wjcc.v3.i7.545
Table 2 Critical factors affecting the decision of starting disease-modifying therapies for multiple sclerosis
Factors suggesting not to start a DMT | CIS with favourable prognostic factors |
RR MS with no relapses in previous two years, no disability, and no evidence of MRI activity (potential “benign” case) | |
Progressive forms of MS with no relapses or evidence of MRI activity | |
Pregnancy planning | |
High risk of low adherence to treatment | |
Factors suggesting to start a first line DMT | CIS with unfavourable prognostic factors |
RR MS with at least one relapse in previous two years but less than two relapses in the last year, low residual disability, and/or active MRI | |
Factors suggesting to start a second line DMT | RR MS with at least 2 disabling relapses in the last year |
Progressive forms of MS with relapses and/or active MRI |
- Citation: Gajofatto A, Benedetti MD. Treatment strategies for multiple sclerosis: When to start, when to change, when to stop? World J Clin Cases 2015; 3(7): 545-555
- URL: https://www.wjgnet.com/2307-8960/full/v3/i7/545.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v3.i7.545