Current status and emerging challenges in the treatment of hepatitis C virus genotypes 4 to 6

doi:10.12998/wjcc.v3.i3.210

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Mar 16, 2015; 3(3): 210-220
Published online Mar 16, 2015. doi: 10.12998/wjcc.v3.i3.210

Table 3 Studies reporting rates of sustained virological response to 48-wk interferon-based combination therapy in patients with hepatitis C genotype 5

Author/Country/Year	No. patients	Regimen	SVR
Legrand-Abravanel/France/2004[75]	12	Standard/Pegylated IFN plus RBV	63.60%
Delwaide/Belgium/2006[74]	6	Standard/Pegylated IFN plus RBV	83%
Bonny/France/2006[78]	87	Standard/Pegylated IFN plus RBV	60%
¹Antaki/Syria/2008[77]	26	Standard/Pegylated IFN plus RBV	54%
D’Heygere/Belgium/2011[79]	38	Standard/Pegylated IFN plus RBV	55.30%
Karatapanis/Greece/2012[29]	10	Pegylated IFN plus RBV	60%
Antaki/Syria/2012[76]	49	Standard/Pegylated IFN plus RBV	49%
Mauss/Germany/2012	24	Pegylated IFN plus RBV	58%
Papastergiou/Greece/2014[81]	27	Pegylated IFN plus RBV	63%

¹Thirteen out of 26 patients received 24 wk of treatment due to personal, financial or medical reasons. IFN: Interferon; RBV: Ribavirin; SVR: Sustained virological response.

Citation: Papastergiou V, Karatapanis S. Current status and emerging challenges in the treatment of hepatitis C virus genotypes 4 to 6. World J Clin Cases 2015; 3(3): 210-220
URL: https://www.wjgnet.com/2307-8960/full/v3/i3/210.htm
DOI: https://dx.doi.org/10.12998/wjcc.v3.i3.210