Promising new treatment targets in patients with fibrosing lung disorders

Table 2 Potential treatment targets in patients with fibrosing lung disease, according to target location

Target	Potential molecular target
Signals from other cells Autocrine signals	Cytokines, survival factors, chemokines, hormones, transmitters, growth factors, extracellular matrix compounds, Wnt, Hedgehog, death factor
Cell surface	Cytokine receptors, receptor tyrosine kinase, G protein-coupled receptors, integrins, Frizzled, Patched, Fas receptor, ion channels
Plasma membrane-cytosol interface	Kinases miRNAs
Cytosol signal transducers	Apoptosis-related proteins
Nucleus	Transcription factors Epigenetic modifiers

miRNA: Micro-ribonucleic acid.