Relationship between longitudinal changes in lipid composition and ischemic stroke among hypertensive patients

Table 2 Baseline characteristics among different in longitudinal changes of dyslipidemia groups, n (%)

	Normal was transformed into normal group	Abnormal was transformed into normal group	Normal was transformed into abnormal group	Abnormal was transformed into abnormal group	P value
Variables	1786	979	883	2446
Age (years)	63.65 ± 13.54	61.23 ± 13.46	63.13 ± 11.71	61.48 ± 12.76	< 0.001
Gender-female	958 (53.6)	455 (46.5)	555 (62.9)	1324 (54.1)	< 0.001
Current smoking	461 (25.8)	277 (28.3)	202 (22.9)	666 (27.3)	0.034
Current drinking	225 (12.6)	149 (15.2)	87 (9.9)	335 (13.7)	0.004
Body mass index (kg/m2)	23.69 ± 3.82	25.39 ± 3.65	24.98 ± 5.31	25.98 ± 3.86	< 0.001
Physical activity					0.006
Never	781 (43.8)	395 (40.3)	351 (39.8)	1020 (41.7)
Occasionally	219 (12.3)	148 (15.1)	89 (10.1)	299 (12.2)
Often	785 (44.0)	436 (44.5)	443 (50.2)	1126 (46.1)
Diabetes	238 (13.4)	211 (21.6)	148 (16.8)	601 (24.6)	< 0.001
Coronary heart disease	17 (1.0)	14 (1.4)	10 (1.1)	44 (1.8)	0.116
Antihypertensive drugs	786 (44.0)	562 (57.4)	533 (60.4)	1567 (64.1)	< 0.001
Hypoglycemic agents	202 (11.3)	200 (20.4)	116 (13.1)	513 (21.0)	< 0.001
Lipid-lowering drugs	0 (0.0)	225 (23.0)	0 (0.0)	784 (32.1)	< 0.001
Total cholesterol (mg/dL)	189.05 ± 27.72	190.17 ± 48.24	202.90 ± 27.18	215.02 ± 54.14	< 0.001
Triglyceride (mg/dL)	101.13 ± 36.47	163.79 ± 122.33	120.26 ± 38.08	228.21 ± 201.58	< 0.001
Low-density lipoprotein cholesterol (mg/dL)	93.02 ± 20.64	94.92 ± 27.47	101.27 ± 21.15	103.35 ± 33.74	< 0.001
High-density lipoprotein cholesterol (mg/dL)	52.66 ± 9.81	43.03 ± 11.78	51.82 ± 11.61	46.68 ± 17.05	< 0.001
Fasting blood glucose (mmol/L)	4.93 ± 1.38	5.14 ± 1.46	4.95 ± 1.22	5.33 ± 1.80	< 0.001
Systolic blood pressure (mmHg)	128.64 ± 15.78	130.32 ± 15.42	131.31 ± 15.99	131.55 ± 15.41	< 0.001
Diastolic blood pressure (mmHg)	79.41 ± 10.17	80.94 ± 9.82	80.13 ± 10.04	81.31 ± 9.83	< 0.001
Estimated glomerular filtration rate (mL/minute/1.73 m2)	96.46 ± 37.20	96.40 ± 35.24	96.20 ± 40.69	94.79 ± 43.15	0.507

Data are presented as mean ± SD or percentage. P values are for the comparison of the difference in longitudinal changes of dyslipidemia groups. Analyzed by one-way analysis of variance.