Relationship between longitudinal changes in lipid composition and ischemic stroke among hypertensive patients

Table 1 Baseline characteristics of participants, n (%)

	Total (n = 6094)	Without ischemic stroke (n = 5951)	With ischemic stroke (n = 143)	P value
Variables
Age (years)	62.32 ± 13.00	62.20 ± 13.04	66.97 ± 10.60	< 0.001
Gender-female	3292 (54.0)	3221 (54.1)	71 (49.7)	0.329
Current smoking	1606 (26.4)	1558 (26.2)	48 (33.6)	0.060
Current drinking	796 (13.1)	780 (13.1)	16 (11.2)	0.583
Body mass index (kg/m2)	25.07 ± 4.17	25.06 ± 4.18	25.46 ± 3.69	0.248
Physical activity				0.065
Never	2547 (41.8)	2474 (41.6)	73 (51.0)
Occasionally	755 (12.4)	738 (12.4)	17 (11.9)
Often	2790 (45.8)	2737 (46.0)	53 (37.1)
Diabetes	1198 (19.7)	1165 (19.6)	33 (23.1)	0.353
Coronary heart disease	85 (1.4)	83 (1.4)	2 (1.4)	1.000
Antihypertensive drugs	3448 (56.6)	3353 (56.3)	95 (66.4)	0.020
Hypoglycemic agents	1031 (16.9)	1004 (16.9)	27 (18.9)	0.603
Lipid-lowering drugs	1009 (16.6)	987 (16.6)	22 (15.4)	0.789
Total cholesterol (mg/dL)	214.47 ± 45.95	214.29 ± 45.82	222.05 ± 50.83	0.046
Triglyceride (mg/dL)	164.98 ± 149.66	164.88 ± 150.17	169.02 ± 127.06	0.744
Low-density lipoprotein cholesterol (mg/dL)	119.85 ± 32.31	119.71 ± 32.13	125.75 ± 38.87	0.027
High-density lipoprotein cholesterol (mg/dL)	48.59 ± 14.12	48.64 ± 14.19	46.45 ± 10.75	0.067
Fasting blood glucose (mmoL/L)	5.13 ± 1.57	5.12 ± 1.55	5.42 ± 2.05	0.023
Systolic blood pressure (mmHg)	130.47 ± 15.65	130.34 ± 15.64	135.72 ± 15.39	< 0.001
Diastolic blood pressure (mmHg)	80.52 ± 9.99	80.49 ± 9.98	81.82 ± 10.18	0.117
Estimated glomerular filtration rate (mL/minute/1.73 m2)	95.74 ± 39.90	95.79 ± 39.33	93.92 ± 58.98	0.581

Data are presented as mean ± SD or percentage. P values are for the comparison of the difference in ischemic stroke conditions.