CXCR4 expression and clinicopathological features of endometrial endometrioid carcinoma with the microcystic, elongated, and fragmented pattern

doi:10.12998/wjcc.v13.i21.103841

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Jul 26, 2025 (publication date) through Apr 27, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Jul 26, 2025; 13(21): 103841
Published online Jul 26, 2025. doi: 10.12998/wjcc.v13.i21.103841

Table 2 Comparison of immunohistochemical expression in different regions of endometrioid endometrial carcinoma with microcystic, elongated, and fragmented infiltration, n (%)

	Cases	High expression of CXCR4	High expression of ER	High expression of PR
EEC main area	60	11 (18.33)	38 (63.33)	42 (70.00)
MELF invasion area	60	49 (81.67)	22 (36.67)	18 (30.00)
P value			0.000	0.000

EEC: Endometrioid endometrial cancer; MELF: Microcystic, elongated, and fragmented; PR: Progesterone receptor; CXCR4: CXC chemokine receptor 4.

Citation: Wang JX, Shen DH, Zhang XB. CXCR4 expression and clinicopathological features of endometrial endometrioid carcinoma with the microcystic, elongated, and fragmented pattern. World J Clin Cases 2025; 13(21): 103841
URL: https://www.wjgnet.com/2307-8960/full/v13/i21/103841.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i21.103841