Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions: A case report

Figure 3 Liquid-based cytology detected ovoid to round cells with hyperchromatic nuclei. Immunohistochemistry exhibited diffuse strong positivity for pan-TRK. A and B: Low power view of uterine cervix (A) (Papanicoalu stain, × 40) A cluster of atypical cells with clumped chromatin is observed, and some cells with low cohesion are scattered individually (B) (Papanicoalu stain, × 100); C and D: The tumor cells were ovoid to round cells with hyperchromatic nuclei formed loosely cohesive clusters without keratinization (C) (Papanicoalu stain, × 400). Pan-TRK staining showed diffuse strong positivity in cytologic specimen (D) (× 400).