Effect of brush rinse on the diagnostic accuracy of biliary stricture evaluation: A multicenter trial

doi:10.12998/wjcc.v13.i15.99212

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May 26, 2025 (publication date) through Jan 23, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. May 26, 2025; 13(15): 99212
Published online May 26, 2025. doi: 10.12998/wjcc.v13.i15.99212

Table 4 Diagnostic performance of the brush-wash vs. sheath-rinse specimens

	Brush-wash (n = 112)	Sheath-rinse (n = 112)	Combined (n = 112)	P value
Accuracy	62.5 (52.9-71.5)	72.3 (63.1-80.4)	74.1 (65.0-81.9)	< 0.001¹
				< 0.001²
				0.157³
Sensitivity	59.2 (49.1-68.8)	69.9 (60.1-78.5)	71.8 (62.1-80.3)	< 0.001¹
				< 0.001²
				0.157³
Specificity	100 (66.3-100)	100 (66.4-100)	100 (66.3-100)	NA
Positive predictive value	100 (94.1-100)	100 (95.0-100)	100 (95.1-100)	NA
Negative predictive value	17.6 (8.4-30.9)	22.5 (10.8-38.5)	23.7 (11.4-40.2)	0.564⁴
				0.483⁵
				0.901⁶

¹Brush-wash vs sheath-rinse.

²Brush-wash vs combined.

³Sheath-rinse vs combined (McNemar’s test).

⁴Brush-wash vs sheath-rinse.

⁵Brush-wash vs combined.

⁶Sheath-rinse vs combined (χ² test).

Values are expressed as n or 95%CI (case/number for analysis). NA: Not applicable.

Citation: So H, Jang SI, Ko SW, Yoon SB, Lee YS, Bang S, Kim M, Choi HJ. Effect of brush rinse on the diagnostic accuracy of biliary stricture evaluation: A multicenter trial. World J Clin Cases 2025; 13(15): 99212
URL: https://www.wjgnet.com/2307-8960/full/v13/i15/99212.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i15.99212