Beta thalassemia syndromes: New insights

doi:10.12998/wjcc.v13.i10.100223

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Apr 6, 2025 (publication date) through Jan 3, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Apr 6, 2025; 13(10): 100223
Published online Apr 6, 2025. doi: 10.12998/wjcc.v13.i10.100223

Table 2 Available therapy for transfusion-dependent beta thalassemia

Treatment	Mode of action
Red blood cell transfusion	Correction of anemia
Deferoxamine	Iron chelation
Deferiprone
Deferasirox
Hematopoietic stem cell transplantation	Replacement with healthy hematopoietic stem cells
Luspatercept	Late-stage erythroid maturation
Exagamglogene autotemcel and lovotibeglogene autotemcel	Autologous genome-modifying/editing based therapy

Citation: Dordevic A, Mrakovcic-Sutic I, Pavlovic S, Ugrin M, Roganovic J. Beta thalassemia syndromes: New insights. World J Clin Cases 2025; 13(10): 100223
URL: https://www.wjgnet.com/2307-8960/full/v13/i10/100223.htm
DOI: https://dx.doi.org/10.12998/wjcc.v13.i10.100223