Low interleukin-10 level indicates a good prognosis in Salmonella enterica serovar typhimurium-induced pediatric hemophagocytic lymphohistiocytosis: A case report

Figure 2 Four-quadrant models for differentiating secondary hemophagocytic lymphohistiocytosis patients with different features. A: Distribution of the patients, 7 controls infected with Salmonella enteric serovar typhimurium (S. typhimurium), and 3 Epstein-Barr virus-hemophagocytic lymphohistiocytosis (EBV-HLH) patients according to a four-quadrant diagram based on the ratio of interleukin-10 (IL-10) to interferon gamma (IFN-γ) > 1.33 or ≤ 1.33 and IFN-γ level > 225 pg/mL or ≤ 225 pg/mL; B: Distribution of the patients, 7 controls infected with S. typhimurium, and 3 EBV-HLH patients according to a four-quadrant diagram based on the ratio of IL-10 to IFN-γ > 1.33 or ≤ 1.33 and IL-10 level > 10 pg/mL or ≤ 10 pg/mL.