Construction of the underlying circRNA-miRNA-mRNA regulatory network and a new diagnostic model in ulcerative colitis by bioinformatics analysis

Figure 5 Model diagnostic factors screened by least absolute shrinkage and selection operator. A: The optimal parameter (λ) selection in the least absolute shrinkage and selection operator model used five-fold cross-validation via minimum criteria. The partial likelihood deviation (binomial deviation) curve was plotted against log(λ). A dashed vertical line was drawn at the optimal value using the smallest criterion and 1 SE of the smallest criterion (1-SE criterion); B: A coefficient distribution map was generated for log(λ), where the optimal λ was the two features with nonzero coefficients.