Immunoglobulin A glomerulonephropathy: A review

Table 1 Adapted from the Oxford classification[6]

Variables	Description
Mesangial hypercellularity	Zero: Less than four mesangial cells are present per mesangial area
	One: Four to five mesangial cells are present per mesangial area
	Two: Six to seven mesangial cells are present per mesangial area
	Three: ≥ eight mesangial cells are present per mesangial area
	The scores obtained for each glomerulus are averaged. If the resulting mean score is less than 0.5, the assigned hypercellularity score is M0. If the mean score is greater than 0.5, the assigned hypercellularity score is M1
Endocapillary hypercellularity	E1: If hypercellularity is present within glomerular
	E0: If no hypercellularity is present within lumens
Segmental glomerulosclerosis	S1: If any part of the glomerular tuft is involved in sclerosis
	S0: If no segmental glomerulosclerosis is present
Tubular atrophy/interstitial fibrosis	T0: Involved cortical area 0% to 25%
	T1: Involved cortical area 26% to 50%
	T2: Involved cortical area > 50%
Crescents	The presence of cellular and/or fibrocellular crescents
	C1: Present in at least one glomerulus
	C2: Present in > 25% of glomeruli
	C0: Absent

Biopsies with fewer than eight glomeruli have a low prognostic yield.