New strategies in the diagnosis and treatment of immune-checkpoint inhibitor-mediated colitis

Figure 3 Grading the severity of immune checkpoint inhibitor-induced colitis and diarrhea and management. After discontinuing immune checkpoint inhibitors, clinical response and mucosal healing assessment are needed, and then biologics, fecal microbiota transplantation or surgery are introduced. Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier (https://smart.servier.com/) is licensed under a Creative Commons Attribution 4.0 Unported License (Supplementary material). FMT: Fecal microbiota transplantation; ICI: Immune checkpoint inhibitors.