Correlative factors of poor prognosis and abnormal cellular immune function in patients with Alzheimer’s disease

Table 1 Clinical data and related characteristics of the Alzheimer’s disease patients

Characteristics	Patients
Sex (male/female)	24/38
Age, mean, range (yr)	71 (55-92)
Interval between onset and hospitalization	87, 5-547
Mean, range (d)
Initial symptom
Hypomnesis, n (%)	19 (30.6)
Apparent personality change	15 (24.2)
Abnormal mental behavior	28 (45.1)
Personality abnormality, n (%)	34 (54.8)
Recent memory deficits, n (%)	54 (87.1)
Hallucination, n (%)	26 (41.9)
Delusion of victimization, n (%)	19 (30.6)
Disturbance of consciousness, n (%)	10 (16.1)
Depressed, n (%)	20 (32.2)
Abnormal EEG results, n (%)	48 (77.4)
(θ + δ)/(α + β) more than 1.8, n (%)	42 (67.7)
Abnormal brain MRI results, n (%)	52 (83.9)
Encephalatrophy, n (%)	43 (69.4)
Abnormality of hippocampus, n (%)	36 (58.1)
Ratio of NAA/Cr decreased, n (%)	59 (95.2)
NLR (median interquartile)	2.25 (1.59-2.97)
Proportion of T lymphocytes in blood	0.55 (0.47-0.63)
Proportion of B lymphocytes in blood	0.13 (0.09-0.18)
Proportion of NK cell in blood	0.11 (0.07-0.17)

EEG: Electroencephalogram; MRI: Magnetic resonance imaging; NLR: Neurtrophil-to-lymphocyte ratio; NAA: N-acetylaspartate; Cr: Creatine; NK: Natural killer.