Acellular dermal matrices in reconstructive surgery; history, current implications and future perspectives for surgeons

Table 6 Clinical evidence examples of the utilization of acellular dermal matrix in abdominal wall reconstruction

Ref.	Year	Title	Note
Zhong et al[96]	2011	Outcomes after abdominal wall reconstruction using acellular dermal matrix: a systematic review	Authors conclude the need for high-level evidence when comparing acellular dermal matrix (ADM) use with other methods to make data-driven recommendations on clinical indications, surgical techniques and outcomes following ADM-assisted abdominal wall reconstruction
Sbitany et al[98]	2015	Outcomes Analysis of Biologic Mesh Use for Abdominal Wall Reconstruction in Clean-Contaminated and Contaminated Ventral Hernia Repair	Authors conclude that single-stage repair of grade 3 hernias performed with component separation and biologic mesh reinforcement is effective and offers a low recurrence rate. The use of biologic mesh allows for avoidance of mesh explantation in instances of wound breakdown or infection. Bridging repairs are associated with a high recurrence rate, as is single-stage repair of grade 4 hernias
Atema et al[99]	2017	Major Complex Abdominal Wall Repair in Contaminated Fields with Use of a Non-cross-linked Biologic Mesh: A Dual-Institutional Experience	Author proposes that the repair of the most challenging abdominal wall defect can be done effectively with combination of a non-cross-linked biologic mesh and component separation technique without the need for mesh removal despite wound infections
Hassan et al[107]	2023	Outcomes of Complex Abdominal Wall Reconstruction After Oncologic Resection: 14-Year Experience at an NCI-Designated Cancer Center	Authors conclude that ADM-assisted abdominal wall repair after extirpative wall resections demonstrated comparable outcomes with primary herniorrhaphy
Giordano et al[108]	2024	Component Separation Decreases Hernia Recurrence Rates in Abdominal Wall Reconstruction with Biologic Mesh	Authors concluded that the component separation technique combined with ADM was associated with fewer hernia recurrences, while surgical site occurrence was similar in long-term follow-up despite additional surgery