Conversion surgery after gemcitabine and cisplatin plus durvalumab for advanced intrahepatic cholangiocarcinoma: A case report

Figure 3 Resection margins. A: Macroscopic findings of mass-forming and periductal-infiltrating intrahepatic cholangiocarcinoma; B: Hematoxylin and eosin (HE) staining of the preoperative biopsy specimen confirming the adenocarcinoma diagnosis; C and D: HE staining of the resected tumor. Small ductular-like structures lined by small nonmucinous cuboidal cells, characteristic findings in small duct type intrahepatic cholangiocarcinomas.