Functional investigation and two-sample Mendelian randomization study of primary biliary cholangitis hub genes

Figure 1 Differentially expressed genes between the primary biliary cholangitis and healthy control groups in the GSE79850 dataset. A: A volcano plot was generated to visualize the differential expression analysis results. Genes that were significantly upregulated in primary biliary cholangitis are depicted in red, genes that were significantly down-regulated are depicted in green, and genes that did not show significant differential expression are depicted in black; B: A heatmap was constructed to illustrate differential expression patterns for genes in the GSE79850 dataset. PBC: Primary biliary cholangitis; DEGs: Differentially expressed genes; GO: Gene ontology; KEGG: Kyoto encyclopedia of genes and genomes.