Toripalimab in combination with chemotherapy effectively suppresses local recurrence and metastatic sarcomatoid renal cell carcinoma: A case report

Figure 2 Pathological examinations in the patient with sarcomatoid renal cell carcinoma. A: 100 ×; B: 200 ×. They displayed a significant proliferation of extremely abnormal spindle cells mixed with tumor giant cells. Additionally, there were areas resembling osteosarcoma and regions with tubular structures. The sarcomatoid component accounts for more than 80% of the tumor; C: The renal cell carcinoma (RCC) component exhibits cytokeratin-pan positivity (400 ×); D: The RCC component was positive for ecological momentary assessment (400 ×); E: Vimentin shows strong immunoreactivity in the sarcomatoid areas and weak immunoreactivity in the renal cell carcinoma areas (400 ×); F: STATB2 exhibits strong immunoreactivity in sarcomatoid areas but not much immunoreactivity in RCC areas (400 ×).