Modifiable factors mediating the effects of educational attainment on gestational diabetes mellitus: A two-step Mendelian randomization study

Table 3 Multivariable mendelian randomization assessing the causal association between each mediator and gestational diabetes mellitus with adjustment for education from inverse variance weighted results

Mediators	nSNPs	Beta	SE	OR	95%CI	P value
WHR	154	0.84	0.17	2.31	1.65 to 3.23	1.00E-06
BMI	420	0.42	0.07	1.53	1.32 to 1.76	5.59E-09
HDL-C	381	-0.28	0.04	0.76	0.70 to 0.82	1.59E-10
Apolipoprotein A-1	358	-0.21	0.05	0.81	0.74 to 0.89	6.08E-06

nSNPs: Number of single-nucleotide polymorphisms; WHR: Waist-to-hip ratio; BMI: Body mass index; HDL-C: High density lipoprotein cholesterol.