Analyze interleukin-1β, interleukin-6, and tumor necrosis factor-α levels in dry eye and the therapeutic effect of cyclosporine A

Table 3 Comparison of Schirmer’s test, tear break-up time and corneal fluorescein staining

Group	n	Time	SIT in mm/5 min	TBUT in s	FL points
Control group	62	Before treatment	6.41 ± 1.32	7.47 ± 1.43	5.18 ± 0.45
		After treatment	9.24 ± 1.97a	7.43 ± 1.65a	2.53 ± 0.35a
Study group	62	Before treatment	6.38 ± 2.14	7.04 ± 1.25	5.14 ± 0.51
		After treatment	12.21 ± 2.41a,c	11.54 ± 1.58a,c	1.25 ± 0.36a,c

Data are mean ± standard deviation.

^aP < 0.05 vs before treatment.

^cP < 0.05 vs control group at the same time.

TBUT: Tear break-up time; FL: Corneal fluorescein staining; SIT: Schirmer’s test.