IgG4-related sclerosing cholangitis associated with essential thrombocythemia: A case report

Table 2 Criteria for diagnosis of essential thrombocythemia

Major criteria	Minor criteria
Platelet count ≥ 450000 per mm3	Presence of clonal marker or of evidence of reactive thrombocytosis
Bone marrow biopsy showing proliferation mainly of the megakaryocytic lineage, with increased numbers of enlarged, mature megakaryocytes with hyperlobated nuclei; no substantial increase or left shift in neutrophil granulopoiesis or erythropoiesis; in rare instances, minor (grade 1) increase in reticulin fibers
Criteria for BCR-ABL1-positive chronic myeloid leukemia, polycythemia vera, primary myelofibrosis, or other myeloid neoplasm not met; JAK2 V617F, CALR, or MPL mutation.

Diagnosis requires all major criteria or the first three major criteria plus a minor criterion. CALR: Calreticulin; JAK2: Janus kinase 2; MPL: Myeloproliferative leukemia.