Effect of dietary with Zhibai dihuang pills and gonadotropin-releasing-hormone-analogue on girls with precocious and rapidly progressive puberty

Table 4 Comparison of ovarian function indicators between the two groups of children (mean ± SD)

Group	Control group	Observation group	t	P value
P (ng/mL)
Before intervention	4.76 ± 1.60	4.83 ± 1.69	0.141	0.891
After intervention	2.94 ± 0.73	2.14 ± 0.64	5.466	0.001
T (nmol/L)
Before intervention	6.78 ± 2.16	6.73 ± 2.22	0.148	0.881
After intervention	4.46 ± 1.44	3.11 ± 1.12	4.757	0.001
E2 (pg/mL)
Before intervention	30.34 ± 5.72	30.85 ± 5.69	0.387	0.706
After intervention	18.76 ± 2.92	11.44 ± 2.75	11.814	0.001
PRL (ng/mL)
Before intervention	12.76 ± 3.51	13.05 ± 3.64	0.370	0.712
After intervention	11.00 ± 2.54	8.93 ± 2.79	3.591	0.001
LH (U/L)
Before intervention	3.16 ± 0.08	3.19 ± 0.08	0.569	0.572
After intervention	2.14 ± 0.36	1.51 ± 0.27	9.314	0.001
FSH (IU/L)
Before intervention	15.22 ± 5.26	15.36 ± 5.15	0.123	0.913
After intervention	8.76 ± 2.57	6.27 ± 2.35	4.615	0.001

P: Progesterone; T: Testosterone; E2: Estradiol; PRL: Prolactin; LH: Luteinizing hormone; FSH: Follicle-stimulating hormone.