Correlation between TEX14 and ADAM17 expressions in colorectal cancer tissues of elderly patients and neoplasm staging, invasion, and metastasis

Table 4 Association between the protein profile of TEX14 and clinical pathology

Pathological features		n	TEX14		χ2 value	P value
			Positive, n = 61	Negative, n = 25
Age	≥ 65 years	54	36 (66.67)	18 (33.33)	1.279	0.258
	< 65 years	32	25 (78.13)	7 (21.88)
Sex	Male	47	35 (74.47)	12 (25.53)	0.629	0.428
	Female	39	26 (66.67)	13 (33.33)
Pathological type	Tubular adenocarcinoma	33	23 (69.70)	10 (30.30)	0.715	0.699
	Villous adenocarcinoma	27	18 (66.67)	9 (33.33)
	Papillary carcinoma	26	20 (76.92)	6 (23.08)
Tumor diameter	≥ 3 cm	46	30 (65.22)	16 (34.78)	1.565	0.211
	< 3 cm	40	31 (77.50)	9 (22.50)
Differentiation degree	Low differentiation	27	15 (55.56)	12 (44.44)	6.602	0.037
	Moderate differentiation	25	17 (68.00)	8 (32.00)
	High differentiation	34	29 (85.29)	5 (14.71)
TNM staging	Stages I-II	37	21 (56.76)	16 (43.24)	6.327	0.012
	Stages III-IV	49	40 (81.63)	9 (18.37)
Lymph node metastasis	Presence	53	43 (83.13)	10 (18.87)	6.972	0.008
	Absence	33	18 (54.55)	15 (45.45)
Infiltration depth	T1 + T2	37	21 (56.76)	16 (43.24)	6.486	0.039
	T3	41	33 (80.49)	8 (19.51)
	T4	8	7 (87.50)	1 (12.5)
Distant metastasis	Presence	46	37 (80.43)	9 (19.57)	4.333	0.037
	Absence	40	24 (60.00)	16 (40.00)

Data are n (%). TEX14: Testis-expressed gene 14.