Effects of pulmonary surfactant combined with noninvasive positive pressure ventilation in neonates with respiratory distress syndrome

Figure 2 Levels of keratin-14 and endothelin-1 before and after treatment. A: There was no significant difference in keratin-14 (KRT-14) in the observation group (4.38 ± 0.84) and in the control group (4.41 ± 0.70) (t = 0.822, P = 0.225). KRT-14 was significantly decreased in both groups after treatment (P < 0.05), and in the observation group (2.99 ± 0.64), the decrease was significantly lower than the control group (3.31 ± 0.51) (t = 3.206, P < 0.002); B: There was no significant difference in endothelin-1 (ET-1) between the observation group (51.34 ± 5.13) and the control group (49.90 ± 4.75) (t = 1.697, P = 0.092). ET-1 was significantly decreased in both groups after treatment (P < 0.05), and it was significantly lower in the observation group (33.29 ± 3.93), than in the control group (41.51 ± 4.48) (t = 11.441, P < 0.001). ^bP < 0.01, ^cP < 0.001.