Clinical effect of botulinum toxin type A combined with autologous fat grafting in patients with nasolabial fold depression

Table 4 Comparison of wrinkle severity rating scale scores (mean ± SD, points)

Group	n	Before operation	1 month after operation	3 months after operation	6 months after operation
Observation group	30	3.52 ± 0.51	1.76 ± 0.52a	1.92 ± 0.49a	2.28 ± 0.46a,b,c
Control group	30	3.64 ± 0.49	2.08 ± 0.49a	2.36 ± 0.29a,b	2.68 ± 0.48a,b,c
t		0.929	2.453	4.233	3.295
P value		> 0.05	< 0.01	< 0.01	< 0.01

^aP < 0.05 compared with before the operation in the same group.

^bP < 0.05 compared with 1 month after the operation in the same group.

^cP < 0.05 compared with 3 months after the operation in the same group.