Serum inflammatory markers in children with Mycoplasma pneumoniae pneumonia and their predictive value for mycoplasma severity

Table 2 Inflammatory cytokines and laboratory findings between severe mycoplasma pneumoniae pneumonia group and mild group

	Severe MPP (n = 80)	Mild MPP (n = 80)	P value
WBC (109/L)	8.5 ± 1.2	7.6 ± 1.4	0.386
CRP (mg/L)	21.4 ± 5.8	5.4 ± 2.6	0.001
PCT (ng/mL)	0.25 ± 0.12	0.05 ± 0.01	0.001
ESR (mm/h)	32.6 ± 7.9	15.8 ± 4.6	0.001
Albumin (g/L)	39.4 ± 4.2	40.5 ± 3.8	0.412
LDH (U/L)	484.2 ± 61.4	246.9 ± 54.6	0.001
D-dimer (mg/L)	1.2 ± 0.6	0.35 ± 0.14	0.001
IL-6 (pg/mL)	25.7 ± 5.6	10.6 ± 3.8	0.001
IL-8 (pg/mL)	102.4 ± 38.8	28.6 ± 14.3	0.001
IL-10 (pg/mL)	36.6 ± 8.9	8.4 ± 2.6	0.001
TNF-α (pg/mL)	26.6 ± 6.5	12.2 ± 4.4	0.001

Data are presented as mean ± SD. SMPP: Severe mycoplasma pneumoniae pneumonia; WBC: White blood cell count; CRP: C-reactive protein; PCT: Procalcitonin; ESR: Erythrocyte sedimentation rate; LDH: Lactic dehydrogenase; IL: Interleukin.