Effect of dienogest treatment on uterine fibroid volume in patients with endometriosis or adenomyosis complicated by uterine fibroids

Table 4 Dienogest treatment for 12 months

	Premedication	Post medication	Value of difference (post medication- premedication)	P value
Maximum diameter of myoma (n = 66, mm)	24.05 ± 13.55	27.08 ± 17.3	3.03	0.017
Myoma volume (n = 66, mm)	10.31 ± 15.01	17.15 ± 25.22	6.84	0.002
Uterine volume (n = 66, mm3)	141.64 ± 98.63	143.71 ± 99.65	2.07	0.797
Maximum diameter of adenomyoma (n = 26, mm)	42.5 ± 14.15	41.46 ± 19.48	-1.04	0.616
Adenomyoma volume (n = 26, mm3)	39.11 ± 36.22	37.55 ± 37.77	-1.57	0.618
Maximum diameter of the cyst (n = 38, mm)	33.11 ± 12.08	21.13 ± 15.5	-11.97	< 0.001
Volume of cysts (n = 38, mm3)	16.22 ± 17.96	7.47 ± 8.36	-8.75	0.002
Endometrial thickness (n = 66, mm)	5.94 ± 3.59	4.49 ± 2.78	-1.55	0.006
CA125 (n = 13, U/mL)	41.6 ± 20.0	22.4 ± 10.9	-19.2	0.002

CA125: Antigen 125.