Effect of dienogest treatment on uterine fibroid volume in patients with endometriosis or adenomyosis complicated by uterine fibroids

Table 3 Dienogest treatment for 6 months

	Premedication	Post medication	Value of difference (post medication- premedication)	P value
Maximum diameter of myoma (n = 83, mm)	23.34 ± 13.63	25.73 ± 15.13	2.40	< 0.001
Myoma volume (n = 83, mm)	10.22 ± 16.83	13.53 ± 19.78	3.31	< 0.001
Uterine volume (n = 83, mm3)	147.06 ± 102.17	144.14 ± 108.64	-2.92	0.67
Maximum diameter of adenomyoma (n = 34, mm)	46.97 ± 14.99	44.68 ± 16.48	-2.3	0.19
Adenomyoma volume (n = 34, mm3)	47.82 ± 40.38	44.61 ± 51.88	-3.21	0.59
Maximum diameter of the cyst (n = 44, mm)	35.48 ± 11.74	27.23 ± 12.31	-8.25	< 0.001
Volume of cysts (n = 44, mm3)	19.02 ± 19.48	9.99 ± 12.79	-9.02	< 0.001
Endometrial thickness (n = 83, mm)	5.89 ± 3.2	4.24 ± 1.94	-1.65	< 0.001
CA125 (n = 13, U/mL)	45.9 ± 19.5	28.2 ± 16.8	-17.7	0.006

CA125: Antigen 125.