Correlation analysis of human papillomavirus E6/E7 mRNA detection with diagnosis, prognosis and recurrence risk in patients with cervical epithelioma

Table 2 Results of the univariate analysis affecting the diagnosis of cervical intraepithelial neoplasia high-grade lesions (%)

Project	CIN grade (n = 52)	CIN grade I (n = 48)	χ2	P value
Age			0.495	0.482
≥ 45	15 (28.8)	17 (35.4)
< 45	37 (71.2)	31 (64.6)
Gravidity			0.031	0.861
≥ 2	16 (30.8)	14 (29.2)
< 2	36 (69.2)	34 (70.8)
Parity			0.495	0.482
≥ 2	15 (28.8)	17 (35.4)
< 2	37 (71.2)	31 (64.6)
HPV (PCR reverse-dot hybridization)			14.408	< 0.001
Positive	36 (69.2)	15 (31.3)
Negative	16 (30.8)	33 (68.7)
HPV E6/E7 mRNA			22.960	< 0.001
Positive	39 (75.0)	13 (27.1)
Negative	13 (25.0)	35 (72.9)

CIN: Cervical intraepithelial neoplasia; HPV: Human papilloma virus; PCR: Polymerase chain reaction.