Inverse relationship between platelet Akt activity and hippocampal atrophy: A pilot case-control study in patients with diabetes mellitus

Figure 2 The relationship between the individual levels of phosphorylated-Akt and the Voxel-based specific regional analysis system for Alzheimer’s disease Z-score. A: Type 2 diabetes mellitus (T2DM) group; B: The control group. The levels of phosphorylated-Akt corrected with those of glyceraldehyde 3-phosphate dehydrogenase in the T2DM group (A) and the control group (B) were plotted against Voxel-based specific regional analysis system for Alzheimer’s disease Z-scores obtained by magnetic resonance imaging. The plotted data were analysed by linear regression analysis. VSRAD: Voxel-based specific regional analysis system for Alzheimer’s disease; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase.