Inverse relationship between platelet Akt activity and hippocampal atrophy: A pilot case-control study in patients with diabetes mellitus

doi:10.12998/wjcc.v12.i2.302

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 12, Issue 2

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (2087)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-4) series, Tables (1-4) series.

Item

Count

PDF

WORD

HTML

1091

Figures (1-4)

173

Tables (1-4)

181

Sum=1556

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

104

Download

367

Sum=471

Jan 16, 2024 (publication date) through Nov 12, 2024

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Clin Cases. Jan 16, 2024; 12(2): 302-313
Published online Jan 16, 2024. doi: 10.12998/wjcc.v12.i2.302

Table 1 Characteristics of the study subjects

Parameters	DM group	Control group
Total number (F/M)	40 (20/20)	15 (8/7)
Age (years)	75.0 ± 7.6	73.4 ± 7.0
DM duration (years)	13.6 ± 11.3	None
Height (cm)	156.7 ± 8.8	158.5 ± 8.3
Weight (kg)	57.0 ± 10.5	57.8 ± 7.1
BMI	23.2 ± 3.8	23.0 ± 2.6
sBP (mmHg)	124.5 ± 19.3	130.0 ± 15.7
dBP (mmHg)	67.8 ± 13.6	74.4 ± 11.6
HbA1c (%)	8.1 ± 1.4^d	5.9 ± 0.2
Glu (mg/dL)	175.0 ± 54.2^d	99.3 ± 13.3
TC (mg/dL)	185.1 ± 33.3	201.6 ± 29.4
TG (mg/dL)	119.1 ± 53.7	110.7 ± 57.0
HDL (mg/dL)	53.6 ± 14.4	61.9 ± 13.7
Plt (× 10⁴/μL)	21.4 ± 5.9	23.8 ± 3.7
VSRAD Z-score	0.841 ± 0.462	0.900 ± 0.489

^dP < 0.01, compared to the control group.

F: Female; M: Male; DM: Diabetes mellitus; BMI: Body mass index; sBP: Systolic blood pressure; dBP: Diastolic blood pressure; HbA1c: Hemoglobin A1c; Glu: Plasma glucose; TC: Total cholesterol; TG: Triglyceride; HDL: High-density lipoprotein; Plt: Platelet counts; VSRAD: Voxel-based specific regional analysis for Alzheimer’s Disease. The data are presented as the mean ± SD.

Citation: Tokuda H, Hori T, Mizutani D, Hioki T, Kojima K, Onuma T, Enomoto Y, Doi T, Matsushima-Nishiwaki R, Ogura S, Iida H, Iwama T, Sakurai T, Kozawa O. Inverse relationship between platelet Akt activity and hippocampal atrophy: A pilot case-control study in patients with diabetes mellitus. World J Clin Cases 2024; 12(2): 302-313
URL: https://www.wjgnet.com/2307-8960/full/v12/i2/302.htm
DOI: https://dx.doi.org/10.12998/wjcc.v12.i2.302