Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

Table 4 Logistic regression analyses of factors associated with venous thromboembolism among patients undergoing hepatectomy

Variables	Univariate analysis			Multivariate analysis
	OR	95%CI	P value	OR	95%CI	P value
Sex (female)	1.0	0.26-3.86	1.0
Age ≥ 70 yr	1.2	0.35-4.19	0.7585
Major hepatectomy	3	0.10-1.09	0.0682
Minimally invasivehepatectomy	3.07	0.89-10.6	0.0755
BMI ≥ 25 kg/m2	1.17	0.34-4.04	0.8078
HT	2.68	0.70-10.2	0.1484
DM	1.29	0.39-4.25	0.6700
Cardiovascular disease	0.72	0.09-5.93	0.7662
Smoking	1.3	0.38-4.49	0.6751
Anticoagulation	1.7	0.25-8.31	0.5157
Ope time ≥ 462 (min)	5.3	1.39-20.3	0.0147	3.37	0.80-14.2	0.0978
Blood loss ≥ 275 (mL)	10	2.12-47.1	0.0036	5.32	1.05-27.0	0.0435
Blood transfusion	4.48e-7		0.9902
DD (POD 5) ≥ 21 (μg/mL)	14.8	3.11-70.1	< 0.0001	10.1	2.04-50.1	0.0046
Complication (≥ CDIIIb)	4.0	0.41-38.8	0.2322

VTE: Venous thromboembolism; OR: Odds ratio; BMI: Body mass index; HT: Hypertension; DM: Diabetes mellitus; POD: Postoperative day; DD: D-dimer; CD: Clavien-Dindo classification; CI: Confidence interval.