Prognostic role of the stromal cell derived factor-1 in patients with hepatitis B virus-related acute-on-chronic liver failure

Figure 4 Increased serum stromal cell derived factor-1 predicted poor prognosis in hepatitis B virus-related acute-on-chronic liver failure patients. Linear correlation of serum stromal cell derived factor-1 (SDF-1) levels with disease severity marker in acute-on-chronic liver failure (ACLF) patients. SDF-1 was positively correlated with A: Total bilirubin; B: International normalized ratio; C: Non-survivors (n = 19) had elevated SDF-1 levels compared with survivors (n = 11) of patients with hepatitis B virus (HBV)-related ACLF; D: Showed the area under the curve (AUC) of the serum SDF-1 level in predicting 28-d mortality of HBV-related ACLF patients. The AUC was 0.722 (95%CI 0.526-0.919). SDF-1: Stromal cell derived factor-1; TBIL: Total bilirubin; INR: International normalized ratio.