Prognostic role of the stromal cell derived factor-1 in patients with hepatitis B virus-related acute-on-chronic liver failure

Figure 2 Immunohistochemical staining for CXCR4 in livers. CXCR4 staining was observed predominantly in the membrane and cytoplasm of bile duct epithelium and hepatic progenitor cells. A: Strongly positive immunostaining in hepatitis B virus-related acute-on-chronic liver failure (ACLF) patients; B: Weakly positive immunostaining in chronic hepatitis B patients; C: Negative immunostaining in healthy controls; D: Comparison of the CXCR4 average absorbance between ACLF group and other groups. A-C: 400 ×. CXCR4: CXC receptor 4; ACLF: Acute-on-chronic liver failure; CHB: Chronic hepatitis B.