Evaluating the efficacy of percutaneous puncture biopsy guided by contrast-enhanced ultrasound for peripheral pulmonary lesions

Table 3 Comparison of diagnostic efficacy of ultrasound-guided puncture biopsy for lung lesions

	CEUS group	Control group	z value	P value
Total number (n = 237)	118	119
Sensitivity (95%CI)	94.7% (88.15-97.71)	89.5% (81.29-94.40)	1.093	0.274
Specificity (95%CI)	95.8% (79.76-99.79)	90.9% (76.43-96.86)	0.796	0.426
AUC (95%CI)	0.952 (0.896-0.983)	0.902 (0.835-0.949)	1.282	0.200
1-5 cm (n = 164)	83	81
Sensitivity (95%CI)	95.4% (87.47-98.76)	95.1% (86.71-98.68)	0.134	0.893
Specificity (95%CI)	94.1% (73.02-99.70)	94.7% (75.36-99.73)	0.081	0.936
AUC (95%CI)	0.949 (0.877-0.986)	0.947 (0.876-0.985)	0.037	0.970
≥ 5 cm (n = 73)	35	38
Sensitivity (95%CI)	92.8% (77.35-98.73)	75.0% (55.10-88.00)	1.178	0.075
Specificity (95%CI)	100% (64.57-100.0)	85.7% (60.06-97.46)	1.051	0.293
AUC (95%CI)	0.964 (0.840-0.998)	0.804 (0.643-0.914)	2.271	0.023

CEUS: Contrast-enhanced ultrasound; AUC: Area under the curve; CI: Confidence interval.