Effects of acetylcysteine on micro-inflammation and pulmonary ventilation in chronic obstructive pulmonary disease exacerbation

Table 5 Lung ventilation function parameters in the treatment and control groups

	FEV1 (L)			FEV1 (% predicted)			FVC (L)			FVC (% predicted)			PEF (L)			PEF (% predicted)
Group	Baseline	End of treatment	Change	Baseline	End of treatment	Change	Baseline	End of treatment	Change	Baseline	End of treatment	Change	Baseline	End of treatment	Change	Baseline	End of treatment	Change
Treatment	1.2 ± 0.4	1.6 ± 0.5	0.4 ± 0.2	38.4 ± 12.8	51.2 ± 16.0	12.8 ± 6.4	2.4 ± 0.8	3.2 ± 1.0	0.8 ± 0.4	72.4 ± 18.4	84.8 ± 22.4	12.4 ± 8.8	2.6 ± 1.0	3.8 ± 1.2	1.2 ± 0.6	58.4 ± 18.4	76.8 ± 22.4	18.4 ± 12.4
Control	1.2 ± 0.4	1.4 ± 0.4	0.2 ± 0.2	36.8 ± 12.4	44.8 ± 12.8	6.4 ± 4.8	2.4 ± 0.8	2.8 ± 0.8	0.4 ± 0.2	70.8 ± 18.0	78.4 ± 20.4	6.4 ± 4.8	2.4 ± 0.8	3.0 ± 0.8	0.6 ± 0.4	56.8 ± 16.4	68.0 ± 18.0	8.4 ± 8.0
Mean difference (95%CI)	0.2 (0.1 to 0.3)			6.4 (4.2 to 8.6)			0.4 (0.2 to 0.6)			6.0 (4.0 to 8.0)			0.6 (0.4 to 0.8)			10.0 (6.8 to 13.2)
P value	< 0.001			< 0.001			< 0.001			< 0.001			< 0.001			< 0.001

FEV1: Forced expiratory volume in one second; FVC: Forced vital capacity; PEF: Peak expiratory flow.