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©The Author(s) 2024.
World J Clin Cases. Jun 26, 2024; 12(18): 3385-3394
Published online Jun 26, 2024. doi: 10.12998/wjcc.v12.i18.3385
Published online Jun 26, 2024. doi: 10.12998/wjcc.v12.i18.3385
Variables | Levels | Training set (n = 294) | Validation Set (n = 143) | χ2/Z | P value |
Recurrence | No | 243 (82.7) | 123 (86.0) | 0.799 | 0.372 |
Yes | 51 (17.3) | 20 (14.0) | |||
Follow up (months) | Median (IQR) | 19.10 (10.40, 29.38) | 18.23 (9.97, 29.03) | -1.007 | 0.314 |
Age (yr) | < 60 | 116 (39.5) | 55 (38.5) | 0.040 | 0.842 |
≥ 60 | 178 (60.5) | 88 (61.5) | |||
Histological type | Ⅰ | 241 (82.0) | 120 (83.9) | 0.253 | 0.615 |
Ⅱ | 53 (18.0) | 23 (16.1) | |||
Smoking | No | 275 (93.5) | 135 (94.4) | 0.125 | 0.724 |
Yes | 19 (6.5) | 8 (5.6) | |||
Hypertension | No | 244 (83.0) | 121 (84.6) | 0.184 | 0.668 |
Yes | 50 (17.0) | 22 (15.4) | |||
ctDNA | Negative | 222 (75.5) | 112 (78.3) | 0.422 | 0.516 |
Positive | 72 (24.5) | 31 (21.7) | |||
Diabetes | No | 267 (90.8) | 127 (88.8) | 0.436 | 0.509 |
Yes | 27 (9.2) | 16 (11.2) | |||
Myometrial invasion | < 1/2 | 119 (40.5) | 63 (44.1) | 0.507 | 0.476 |
≥ 1/2 | 175 (59.5) | 80 (55.9) | |||
Grade | G1 | 98 (33.3) | 54 (37.8) | 0.885 | 0.642 |
G2 | 145 (49.3) | 67 (46.9) | |||
G3 | 51 (17.4) | 22 (15.3) | |||
FIGO | Ⅰ | 88 (29.9) | 44 (30.8) | 0.719 | 0.869 |
Ⅱ | 71 (24.1) | 32 (22.4) | |||
Ⅲ | 94 (32.1) | 50 (35.0) | |||
Ⅳ | 41 (13.9) | 17 (11.8) | |||
Postoperative adjuvant therapy | No | 90 (30.6) | 48 (33.6) | 0.389 | 0.533 |
Yes | 204 (69.4) | 95 (66.4) | |||
Lymph node metastasis | No | 173 (58.8) | 81 (56.6) | 0.191 | 0.662 |
Yes | 121 (41.2) | 62 (43.4) | |||
Postoperative CA125 (U/mL) | < 19 | 174 (59.2) | 84 (58.7) | 0.008 | 0.930 |
≥ 19 | 120 (40.8) | 59 (41.3) |
- Citation: Liu Y, Lu XN, Guo HM, Bao C, Zhang J, Jin YN. Development and validation of a circulating tumor DNA-based optimization-prediction model for short-term postoperative recurrence of endometrial cancer. World J Clin Cases 2024; 12(18): 3385-3394
- URL: https://www.wjgnet.com/2307-8960/full/v12/i18/3385.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v12.i18.3385